Download e-book for kindle: Atlas of Peripheral Blood: The Primary Diagnostic Tool by Irma Pereira MT (ASCP) SH, Tracy I. George MD, Daniel A.

By Irma Pereira MT (ASCP) SH, Tracy I. George MD, Daniel A. Arber MD

ISBN-10: 0781777801

ISBN-13: 9780781777803

This publication might be a full-color atlas of either benign and neoplastic proliferations within the blood. The e-book will illustrate the morphologic positive aspects on peripheral blood smears of some of the issues and the textual content will specialize in diagnostic standards, differential analysis and smooth category terminology. The e-book can be used as a stand-alone source and may be important to trainees and clinicians that commonly evaluate peripheral blood smears. The publication might be observed by way of an online photo financial institution containing a variety of extra full-color pictures of many of the disorders.

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Extra info for Atlas of Peripheral Blood: The Primary Diagnostic Tool

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4). The disease may be idiopathic or related to other conditions such as lymphoma or autoimmune disorders, particularly systemic lupus erythematosus. Drugs such as penicillin, 6-mercaptopurine, ribavirin, and a-methyldopa may also promote warm autoantibody production, a process known as druginduced immune hemolysis. 1 Mechanism of microangiopathic hemolysis. Depending on where the RBC folds over the fibrin strand, different sizes of fragmented red cells will be present in the circulation. As shown in this example, these could be the small schistocyte or the larger helmet cell.

11). 3 Large three-dimensional RBC aggregates are readily visible at low power and indicate the presence of cold autoagglutinins. in affected neonates and infants who may present with hydrops fetalis, jaundice, splenomegaly, and severe hemolytic anemia requiring transfusions. PK deficiency is distinguished as one of the nonspherocytic hemolytic anemias. Cases with echinocytes, acanthocytes, bite cells, and microspherocytes have all been documented. The reticulocyte count is markedly increased in these patients (Fig.

3. This phenomenon may cause a falsely decreased RBC count with a normal hemoglobin and high mean corpuscular volume (MCV) value on automated hematology analyzers due to the instrument counting clumps of red cells as single cells with increased diameters, and hence a falsely high MCV. Agglutination is reversed by warming the blood to 37°C. Mycoplasma pneumoniae infection or lymphoma may prompt production of cold autoagglutinins. 2. Warm autoagglutinins: This condition is mediated predominately by IgG antibodies.

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Atlas of Peripheral Blood: The Primary Diagnostic Tool by Irma Pereira MT (ASCP) SH, Tracy I. George MD, Daniel A. Arber MD

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